Immune Deficiency

Many SLOS kids get colds and are sick quite often. It may or may not be as much as healthy kids, but SLOS don't seem to be able to handle the colds as well especially if they are g-tube fed or have a hard time clearing their throats and have a lot of mucous buildup or nasal drainage. In some cases the children have been diagnosed with Common Variable Immune Deficiency or Selective Antibody Immune Deficiency in which the children cannot break down certain RBC and polysacharides, and even after vaccinations show no titers; the treatment for which is IVIG therapy. Some children are home-schooled to help combat this issue. For some children, when the vomiting or diarrhea becomes severe for several days or if there is a constant fever over 101 degrees, certain doctors recommend using Stress Dose Steroids. A description of which is in the next section on medications.

The following is an article about IVIG and one of our SLO children
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15877207&query_hl=1&itool=pubmed_docsum