Simvastatins

Medications in this category are on trial in several places including Oregon (OHSU) and in Maryland (KKI). Although these meds are more commonally used to lower cholesterol, it seems that in some doses, it lowers the 7DHC levels while helping to increase sterol cholesterol. It also appears to cross the blood/brain barrier. However, these trials are only being done on the mildest of cases due to the potential worsening of affects in the severe cases and therefore this treatment is not recommeded for those children with severe levels of cholesterol. The liver and kidneys are watched closely and spinal taps are done regularly. Zocor or Lomastatin are some drugs used.